Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ eIF-2α Inhibitor II, Sal003
The eIF-2α Inhibitor II, Sal003, also referenced under CAS 301359-91-1, controls the biological activity of eIF-2α. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ BLM Helicase Inhibitor, ML216
A cell-permeable pyridinyl-thiadiazolylurea compound that selectively blocks Bloom's syndrome protein (BLM) helicase activity of both full-length as well as truncated BLM636-1298 forms (IC50
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set IV
A cocktail of three phosphatase inhibitors for the inhibition of both serine/threonine and alkaline phosphatases.
MilliporeSigma™ Calbiochem™ TIRAP Inhibitor Peptide, Cell-Permeable
The TIRAP Inhibitor Peptide, Cell-Permeable blocks LPS-, but not CpG-induced NF-κB activation. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Adenosine A2A Receptor Antagonist I, ZM 241385
A highly potent, selective, non-xanthine adenosine A2A receptor antagonist (Ki = 800 pM for human adenosine A2AR stably expressed in HEK-293 cells).
MilliporeSigma™ Calbiochem™ MICAL-2 Inhibitor II, CCG-203971
A cell-permeable, restricted form of CCG-1423 with enhanced potency (IC50 = 4.2 μM vs 16.6 μM for PC-3 cell migration), but reduced off-target toxicity.
MilliporeSigma™ Calbiochem™ Piceatannol
A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC50 = 3μM), PKC (IC50 = 8μM), MLCK (IC50 = 12μM).
MilliporeSigma™ Calbiochem™ DIDS, Disodium Salt
Binds covalently and irreversibly to the outer surface of human erythrocyte membranes.
MilliporeSigma™ Calbiochem™ GPR55 Receptor Antagonist, CID16020046
A selective antagonist of G protein-coupled receptor 55 (GPR55) that blocks lipid L-a-lysophosphatidylinositol (LPI, Cat
MilliporeSigma™ Calbiochem™ Focal Adhesion Kinase Inhibitor I
The Focal Adhesion Kinase Inhibitor I, also referenced under CAS 4506-66-5, controls the biological activity of Foca Adhesion Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Pre-mRNA Splicing Inhibitor, Isoginkgetin
The Pre-mRNA Splicing Inhibitor, Isoginkgetin, also referenced under CAS 548-19-6, blocks the spliceosome-meidated splicing process.
MilliporeSigma™ Calbiochem™ REV-ERBα Agonist, GSK4112
The REV-ERBα Agonist, GSK4112 controls the biological activity of REV-ERBα. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphate, Sodium Salt
Important intracellular second messenger implicated in the action of nitric oxide in many cell types.
MilliporeSigma™ Calbiochem™ Sulindac Sulfide
A cell-permeable, active metabolite of Sulindac.
MilliporeSigma™ Calbiochem™ Cathepsin D Substrate I
Useful as a substrate for the determination of cathepsin D activity.