Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ clasto-Lactacystin β-Lactone
A highly specific, cell-permeable, and irreversible 20S proteasome inhibitor.
MilliporeSigma™ Calbiochem™ S1P4 Receptor Antagonist, CYM50358
The S1P4 Receptor Antagonist, CYM50358 controls the biological activity of S1P4 Receptor. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ APE1 Inhibitor III
The APE1 Inhibitor III controls the biological activity of APE1. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Orai1/CRAC Blocker, Cpd5J-4
A non-toxic thiourea derivative that acts as a blocker of Orai1, the pore subunit of Ca2+-release-activated Ca2+ (CRAC) in T
MilliporeSigma™ Calbiochem™ Granzyme B Inhibitor IV
The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ L- Buthionine Sulfoximine
A cell-permeable, sulfoximine based compound that acts a potent, fast acting, irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels
MilliporeSigma™ Calbiochem™ SRT1720
SRT1720, CAS 925434-55-5, is a cell-permeable inhibitor of the mitochondrial SIRT3. Inhibition is AceCS2-competitive (Ki = 0.56μM; Km = 2.44μM), but NAD+-uncompetitive (Ki = 0.34μM; Km = 280μM).
MilliporeSigma™ Calbiochem™ Histone Deacetylase Inhibitor II
The Histone Deacetylase Inhibitor II, also referenced under CAS 174664-65-4, controls the biological activity of Histone Deacetylase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Vigabatrin
A selective, irreversible inhibitor of GABA transaminase with antiepileptic properties
MilliporeSigma™ Calbiochem™ 5-Lipoxygenase Inhibitor, MK591
MK591; MK0591; 5-LOX inhibitor, 5- Lipoxygenase inhibitor, FLAP
MilliporeSigma™ Calbiochem™ Antipain, Hydrochloride
Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes.
MilliporeSigma™ Calbiochem™ βARK1 Inhibitor
The βARK1 Inhibitor, also referenced under CAS 24269-96-3, controls the biological activity of βARK1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Pifithrin-α, p-Nitro, Cyclic
A cell-permeable p53 inhibitor that exhibits 10-fold higher potency and 50% longer half-life than Pifithrin-α.
MilliporeSigma™ Calbiochem™ SB 290157
A selective, high affinity, competitive antagonist of the anaphylatoxin C3a receptor. Does not antagonize C5aR or other chemotactic GPCRs.
MilliporeSigma™ Calbiochem™ CaCC Blocker IV, Benzbromarone
A cell-permeable uricosuric agent that, in addition to its known efficacy in gout treatment, acts as a reversible CaCC blocker and is reported to be more potent than NFA (Cat